YxaF protein (Legionella waltersii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

YxaF

TetR family transcriptional regulator. (186 aa)

Predicted Functional Partners:

Lwal_3244

0.780

EryA

0.728

Lwal_2663

0.664

gacS/letS

0.614

Gmr_3

0.607

Cph2_6

0.607

Gmr_4

0.607

pth

0.581

ftsZ

0.446

UvrY

0.417

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cph2_6	EryA	Lwal_3024	Lwal_0942	Inner membrane protein.	Polyketide synthase module.	0.694
Cph2_6	Gmr_3	Lwal_3024	Lwal_2767	Inner membrane protein.	Regulatory protein (GGDEF domain).	0.993
Cph2_6	Gmr_4	Lwal_3024	Lwal_3050	Inner membrane protein.	GGDEF domain-containing sensory box protein.	0.993
Cph2_6	Lwal_2663	Lwal_3024	Lwal_2663	Inner membrane protein.	Saframycin Mx1 synthetase B.	0.677
Cph2_6	UvrY	Lwal_3024	Lwal_1314	Inner membrane protein.	Response regulator GacA.	0.848
Cph2_6	YxaF	Lwal_3024	Lwal_3243	Inner membrane protein.	TetR family transcriptional regulator.	0.607
Cph2_6	ftsZ	Lwal_3024	Lwal_1269	Inner membrane protein.	Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	0.610
Cph2_6	gacS/letS	Lwal_3024	Lwal_0618	Inner membrane protein.	Transmission sensor LetS.	0.996
EryA	Cph2_6	Lwal_0942	Lwal_3024	Polyketide synthase module.	Inner membrane protein.	0.694
EryA	Gmr_3	Lwal_0942	Lwal_2767	Polyketide synthase module.	Regulatory protein (GGDEF domain).	0.694
EryA	Gmr_4	Lwal_0942	Lwal_3050	Polyketide synthase module.	GGDEF domain-containing sensory box protein.	0.694
EryA	Lwal_2663	Lwal_0942	Lwal_2663	Polyketide synthase module.	Saframycin Mx1 synthetase B.	0.999
EryA	UvrY	Lwal_0942	Lwal_1314	Polyketide synthase module.	Response regulator GacA.	0.608
EryA	YxaF	Lwal_0942	Lwal_3243	Polyketide synthase module.	TetR family transcriptional regulator.	0.728
EryA	ftsZ	Lwal_0942	Lwal_1269	Polyketide synthase module.	Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	0.637
EryA	gacS/letS	Lwal_0942	Lwal_0618	Polyketide synthase module.	Transmission sensor LetS.	0.938
Gmr_3	Cph2_6	Lwal_2767	Lwal_3024	Regulatory protein (GGDEF domain).	Inner membrane protein.	0.993
Gmr_3	EryA	Lwal_2767	Lwal_0942	Regulatory protein (GGDEF domain).	Polyketide synthase module.	0.694
Gmr_3	Gmr_4	Lwal_2767	Lwal_3050	Regulatory protein (GGDEF domain).	GGDEF domain-containing sensory box protein.	0.991
Gmr_3	Lwal_2663	Lwal_2767	Lwal_2663	Regulatory protein (GGDEF domain).	Saframycin Mx1 synthetase B.	0.677