| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOH18053.1 | dnaN | ACZ92_17995 | ACZ92_03385 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.966 |
| KOH18053.1 | recA | ACZ92_17995 | ACZ92_20950 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
| KOH18053.1 | xni | ACZ92_17995 | ACZ92_12690 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.866 |
| KOH18246.1 | KOH18345.1 | ACZ92_19100 | ACZ92_19645 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| KOH18246.1 | dnaA | ACZ92_19100 | ACZ92_03390 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.697 |
| KOH18246.1 | dnaE | ACZ92_19100 | ACZ92_19700 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
| KOH18246.1 | dnaN | ACZ92_19100 | ACZ92_03385 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.996 |
| KOH18246.1 | gyrB | ACZ92_19100 | ACZ92_03375 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.518 |
| KOH18246.1 | holA | ACZ92_19100 | ACZ92_12555 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
| KOH18246.1 | recA | ACZ92_19100 | ACZ92_20950 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.602 |
| KOH18246.1 | xni | ACZ92_19100 | ACZ92_12690 | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.577 |
| KOH18345.1 | KOH18246.1 | ACZ92_19645 | ACZ92_19100 | 3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| KOH18345.1 | dnaE | ACZ92_19645 | ACZ92_19700 | 3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.990 |
| KOH18345.1 | dnaN | ACZ92_19645 | ACZ92_03385 | 3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.994 |
| KOH18345.1 | holA | ACZ92_19645 | ACZ92_12555 | 3'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| dnaA | KOH18246.1 | ACZ92_03390 | ACZ92_19100 | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.697 |
| dnaA | dnaE | ACZ92_03390 | ACZ92_19700 | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
| dnaA | dnaN | ACZ92_03390 | ACZ92_03385 | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
| dnaA | gyrB | ACZ92_03390 | ACZ92_03375 | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| dnaA | recA | ACZ92_03390 | ACZ92_20950 | Chromosomal replication initiation protein; Binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.736 |
