| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOH17316.1 | KOH18247.1 | ACZ92_22180 | ACZ92_19105 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| KOH17316.1 | KOH18683.1 | ACZ92_22180 | ACZ92_21290 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.423 |
| KOH17316.1 | KOH21535.1 | ACZ92_22180 | ACZ92_12850 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.811 |
| KOH17316.1 | argS | ACZ92_22180 | ACZ92_11850 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | arginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.447 |
| KOH17316.1 | gmk | ACZ92_22180 | ACZ92_14085 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.936 |
| KOH17316.1 | guaA | ACZ92_22180 | ACZ92_05185 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| KOH17316.1 | map | ACZ92_22180 | ACZ92_19780 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine aminopeptidase; Catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
| KOH17316.1 | pyrG | ACZ92_22180 | ACZ92_21015 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| KOH17316.1 | tet(34) | ACZ92_22180 | ACZ92_12815 | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.933 |
| KOH18247.1 | KOH17316.1 | ACZ92_19105 | ACZ92_22180 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| KOH18247.1 | KOH21535.1 | ACZ92_19105 | ACZ92_12850 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.794 |
| KOH18247.1 | gmk | ACZ92_19105 | ACZ92_14085 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.961 |
| KOH18247.1 | guaA | ACZ92_19105 | ACZ92_05185 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| KOH18247.1 | pyrG | ACZ92_19105 | ACZ92_21015 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.539 |
| KOH18247.1 | tet(34) | ACZ92_19105 | ACZ92_12815 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.979 |
| KOH18683.1 | KOH17316.1 | ACZ92_21290 | ACZ92_22180 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.423 |
| KOH18683.1 | guaA | ACZ92_21290 | ACZ92_05185 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase; Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.970 |
| KOH18683.1 | tet(34) | ACZ92_21290 | ACZ92_12815 | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.918 |
| KOH21535.1 | KOH17316.1 | ACZ92_12850 | ACZ92_22180 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.811 |
| KOH21535.1 | KOH18247.1 | ACZ92_12850 | ACZ92_19105 | Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.794 |