Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iscRRrf2 family transcriptional regulator; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (168 aa)    
Predicted Functional Partners:
hscB
Cobalamin 5'-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HscB family.
 
  
 0.989
KOH22561.1
Scaffolding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.981
iscA
Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.916
KOH22563.1
tRNA (cytidine/uridine-2'-O-)-methyltransferase; Catalyzes the fromation of 2'O-methylated cytidine or 2'O-methylated uridine at position 32 in tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.914
iscX
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.908
nfuA
Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
  
 0.905
fdx
2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.824
hscA
Chaperone protein HscA; Involved in the maturation of iron-sulfur cluster-containing proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.822
KOH17308.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.757
araC
Positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.753
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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