Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KOH20893.1Shikimate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)    
Predicted Functional Partners:
KOH18732.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.617
KOH22570.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.602
KOH17316.1
Guanosine 5'-monophosphate oxidoreductase; Catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
       0.528
pilW
Pilus assembly protein PilW; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
  0.522
KOH25069.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
KOH20894.1
BCCT transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BCCT transporter (TC 2.A.15) family.
       0.504
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.500
KOH20905.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.491
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
Server load: low (18%) [HD]