Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KOH21118.1DNA-3-methyladenine glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)    
Predicted Functional Partners:
KOH24682.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
 0.898
guaA
GMP synthase; Contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.716
KOH17222.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      0.644
KOH24683.1
3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.597
mutY
Adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.589
KOH22409.1
Multidrug transporter AcrB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.528
KOH21119.1
Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.528
vmeG
Acriflavin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.528
pspC
Phage-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
pspB
Phage-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
Server load: low (18%) [HD]