STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOH21142.1Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.974
KOH21018.1
Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.943
tmk
Thymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.941
KOH17291.1
Cell division protein DedD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.936
KOH18469.1
Thymidine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.935
deoD
Purine nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.926
deoD-2
Purine nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PNP/UDP phosphorylase family.
  
 
 0.926
KOH21295.1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.916
KOH17377.1
Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.916
KOH22447.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
 
  
  0.915
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.