Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
purRTranscriptional regulator; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (334 aa)    
Predicted Functional Partners:
GltB
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.786
KOH17373.1
Ribokinase; Catalyzes the formation of D-ribose 5-phosphate from ribose; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
  
 0.608
KOH21239.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.583
pdhR
Transcriptional regulator PdhR; Activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.568
asnC
Transcriptional repressor of asnA which codes for aspartate-ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.540
xapA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
      
 0.535
KOH21240.1
Molecular chaperone TorD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
KOH21242.1
DNA transformation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
KOH21243.1
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
KOH21244.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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