node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KOH18505.1 | KOH19478.1 | ACZ92_20555 | ACZ92_14735 | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.592 |
KOH18505.1 | cobA-2 | ACZ92_20555 | ACZ92_23030 | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.611 |
KOH18505.1 | hemA | ACZ92_20555 | ACZ92_12370 | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
KOH18505.1 | hemB | ACZ92_20555 | ACZ92_13810 | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.992 |
KOH18505.1 | hemC | ACZ92_20555 | ACZ92_16015 | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.951 |
KOH19405.1 | hemA | ACZ92_14295 | ACZ92_12370 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.813 |
KOH19405.1 | hemB | ACZ92_14295 | ACZ92_13810 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.887 |
KOH19405.1 | hemC | ACZ92_14295 | ACZ92_16015 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.855 |
KOH19478.1 | KOH18505.1 | ACZ92_14735 | ACZ92_20555 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.592 |
KOH19478.1 | cobA-2 | ACZ92_14735 | ACZ92_23030 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | 0.903 |
KOH19478.1 | hemA | ACZ92_14735 | ACZ92_12370 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | glutamyl-tRNA reductase; Catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
KOH19478.1 | hemB | ACZ92_14735 | ACZ92_13810 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.857 |
KOH19478.1 | hemC | ACZ92_14735 | ACZ92_16015 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.987 |
cobA-2 | KOH18505.1 | ACZ92_23030 | ACZ92_20555 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.611 |
cobA-2 | KOH19478.1 | ACZ92_23030 | ACZ92_14735 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
cobA-2 | hemA | ACZ92_23030 | ACZ92_12370 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | glutamyl-tRNA reductase; Catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.762 |
cobA-2 | hemB | ACZ92_23030 | ACZ92_13810 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.864 |
cobA-2 | hemC | ACZ92_23030 | ACZ92_16015 | uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |
cobQ | hemA | ACZ92_23240 | ACZ92_12370 | Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | glutamyl-tRNA reductase; Catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.806 |
cobQ | hemB | ACZ92_23240 | ACZ92_13810 | Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | 0.793 |