| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOH17421.1 | KOH18053.1 | ACZ92_22825 | ACZ92_17995 | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.401 |
| KOH17421.1 | KOH20626.1 | ACZ92_22825 | ACZ92_13175 | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.641 |
| KOH17421.1 | KOH20878.1 | ACZ92_22825 | ACZ92_08895 | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| KOH17421.1 | recA | ACZ92_22825 | ACZ92_20950 | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.771 |
| KOH17421.1 | recQ | ACZ92_22825 | ACZ92_00130 | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| KOH17421.1 | xni | ACZ92_22825 | ACZ92_12690 | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.897 |
| KOH18053.1 | KOH17421.1 | ACZ92_17995 | ACZ92_22825 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exonuclease SbcD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.401 |
| KOH18053.1 | KOH19547.1 | ACZ92_17995 | ACZ92_15145 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.401 |
| KOH18053.1 | KOH20626.1 | ACZ92_17995 | ACZ92_13175 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
| KOH18053.1 | KOH20878.1 | ACZ92_17995 | ACZ92_08895 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.863 |
| KOH18053.1 | KOH21090.1 | ACZ92_17995 | ACZ92_10165 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.414 |
| KOH18053.1 | dnaN | ACZ92_17995 | ACZ92_03385 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.985 |
| KOH18053.1 | mutS | ACZ92_17995 | ACZ92_20960 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA mismatch repair protein MutS; This protein performs the mismatch recognition step during the DNA repair process; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.721 |
| KOH18053.1 | recA | ACZ92_17995 | ACZ92_20950 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.815 |
| KOH18053.1 | recQ | ACZ92_17995 | ACZ92_00130 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.438 |
| KOH18053.1 | xni | ACZ92_17995 | ACZ92_12690 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.968 |
| KOH19547.1 | KOH18053.1 | ACZ92_15145 | ACZ92_17995 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.401 |
| KOH19547.1 | KOH20626.1 | ACZ92_15145 | ACZ92_13175 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.641 |
| KOH19547.1 | KOH20878.1 | ACZ92_15145 | ACZ92_08895 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| KOH19547.1 | recA | ACZ92_15145 | ACZ92_20950 | Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.764 |