Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KOH21509.123S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)    
Predicted Functional Partners:
KOH21510.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.957
gcvA
Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LysR transcriptional regulatory family.
      0.901
KOH21511.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.868
KOH18209.1
Nucleoid-associated protein NdpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.721
nfuA
Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.563
KOH18596.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0149 family.
  
    0.533
KOH21044.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.515
KOH21513.1
tRNA s(4)U8 sulfurtransferase; Catalyzes the conversion of uridine to 4-thiouridinine tRNA; also required for the synthesis of the thiazole moiety; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.513
mreD
Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.488
yceD
Ribosomal protein L32p; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.484
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
Server load: low (12%) [HD]