Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KOH21545.1Sodium:glutamate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (424 aa)    
Predicted Functional Partners:
rhtB
Homoserine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.819
KOH22019.1
Sodium:solute symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.780
dnaK
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.751
sdhD
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.684
KOH18520.1
Ammonium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.670
KOH22286.1
Iron ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.610
KOH19622.1
Vitamin B12-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.604
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
       0.528
ppnK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.528
GltB
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.494
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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