Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argRArginine repressor; Regulates arginine biosynthesis genes. (156 aa)    
Predicted Functional Partners:
argA
N-acetylglutamate synthase; Catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.937
argH
Amino-acid acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.925
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.921
KOH22035.1
Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.902
KOH20653.1
Catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.890
argD
Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
  
 0.839
fabR
Transcriptional regulator; Negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.803
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
 
  
 0.786
fadR
GntR family transcriptional regulator; Multifunctional regulator of fatty acid metabolism.
  
  
 0.781
nrdR
NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.753
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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