| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOH17485.1 | KOH17814.1 | ACZ92_23220 | ACZ92_16580 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| KOH17485.1 | KOH17992.1 | ACZ92_23220 | ACZ92_17630 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
| KOH17485.1 | aspA-2 | ACZ92_23220 | ACZ92_08360 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |
| KOH17485.1 | gltA | ACZ92_23220 | ACZ92_11935 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.902 |
| KOH17485.1 | mdh | ACZ92_23220 | ACZ92_14880 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.945 |
| KOH17485.1 | pckA | ACZ92_23220 | ACZ92_13920 | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.872 |
| KOH17814.1 | KOH17485.1 | ACZ92_16580 | ACZ92_23220 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| KOH17814.1 | KOH17992.1 | ACZ92_16580 | ACZ92_17630 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| KOH17814.1 | KOH18563.1 | ACZ92_16580 | ACZ92_20880 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
| KOH17814.1 | KOH21055.1 | ACZ92_16580 | ACZ92_09950 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
| KOH17814.1 | KOH21934.1 | ACZ92_16580 | ACZ92_07860 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
| KOH17814.1 | acnB | ACZ92_16580 | ACZ92_20655 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |
| KOH17814.1 | aspA-2 | ACZ92_16580 | ACZ92_08360 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| KOH17814.1 | gltA | ACZ92_16580 | ACZ92_11935 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. | 0.924 |
| KOH17814.1 | mdh | ACZ92_16580 | ACZ92_14880 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.991 |
| KOH17814.1 | pckA | ACZ92_16580 | ACZ92_13920 | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.936 |
| KOH17992.1 | KOH17485.1 | ACZ92_17630 | ACZ92_23220 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
| KOH17992.1 | KOH17814.1 | ACZ92_17630 | ACZ92_16580 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| KOH17992.1 | KOH18563.1 | ACZ92_17630 | ACZ92_20880 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| KOH17992.1 | KOH21055.1 | ACZ92_17630 | ACZ92_09950 | Catalyzes the formation of fumarate from malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.963 |
