node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KOH18254.1 | KOH19512.1 | ACZ92_19145 | ACZ92_14920 | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
KOH18254.1 | KOH22431.1 | ACZ92_19145 | ACZ92_07320 | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
KOH18254.1 | glyA | ACZ92_19145 | ACZ92_12605 | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.716 |
KOH18254.1 | purH | ACZ92_19145 | ACZ92_03230 | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.502 |
KOH18254.1 | thyA | ACZ92_19145 | ACZ92_15795 | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.858 |
KOH19512.1 | KOH18254.1 | ACZ92_14920 | ACZ92_19145 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
KOH19512.1 | KOH22431.1 | ACZ92_14920 | ACZ92_07320 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
KOH19512.1 | MetH | ACZ92_14920 | ACZ92_13000 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
KOH19512.1 | fmt | ACZ92_14920 | ACZ92_03615 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.936 |
KOH19512.1 | gcvT | ACZ92_14920 | ACZ92_07185 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
KOH19512.1 | glyA | ACZ92_14920 | ACZ92_12605 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.930 |
KOH19512.1 | purH | ACZ92_14920 | ACZ92_03230 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
KOH19512.1 | purN | ACZ92_14920 | ACZ92_19615 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.920 |
KOH19512.1 | purU | ACZ92_14920 | ACZ92_11840 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). | 0.917 |
KOH19512.1 | thyA | ACZ92_14920 | ACZ92_15795 | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.998 |
KOH22431.1 | KOH18254.1 | ACZ92_07320 | ACZ92_19145 | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
KOH22431.1 | KOH19512.1 | ACZ92_07320 | ACZ92_14920 | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
KOH22431.1 | MetH | ACZ92_07320 | ACZ92_13000 | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
KOH22431.1 | gcvT | ACZ92_07320 | ACZ92_07185 | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
KOH22431.1 | glyA | ACZ92_07320 | ACZ92_12605 | Formate--tetrahydrofolate ligase; Catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.969 |