Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tsaDUGMP family protein; Universal genome maintenance protein; Kae1/Qri7/OSGEP/YgjD family protein; in Archaea, some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex; kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32); in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32; the protein is essential in Escherichia coli and Bacillus subtilis; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)    
Predicted Functional Partners:
tsaB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.981
KOH21974.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.937
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
   
 0.791
tsaC
tRNA threonylcarbamoyladenosine biosynthesis protein RimN; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
 
 0.784
KOH19558.1
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
   
 0.757
rpsU
30S ribosomal protein S21; A small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family.
  
  
 0.752
pheT
phenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.749
KOH19562.1
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.739
KOH19560.1
glutamyl-tRNA amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.716
KOH18059.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.696
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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