STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOH19584.1Serine endoprotease DegQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)    
Predicted Functional Partners:
KOH18590.1
Anti-sigma E factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]
 
 
 0.857
glpK
Converts glycerol and ADP to glycerol-3-phosphate and ADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.784
pspC
Phage-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.609
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.592
KOH19583.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.588
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.586
pnp
Polynucleotide phosphorylase/polyadenylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.571
rplI
50S ribosomal protein L9; In Escherichia coli this protein is wrapped around the base of the L1 stalk; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.547
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
   
 0.512
KOH22352.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.510
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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