| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KOH18053.1 | KOH18127.1 | ACZ92_17995 | ACZ92_18405 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
| KOH18053.1 | KOH18387.1 | ACZ92_17995 | ACZ92_19885 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| KOH18053.1 | KOH20626.1 | ACZ92_17995 | ACZ92_13175 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.663 |
| KOH18053.1 | KOH20878.1 | ACZ92_17995 | ACZ92_08895 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.863 |
| KOH18053.1 | KOH21264.1 | ACZ92_17995 | ACZ92_11170 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.789 |
| KOH18053.1 | RnhB | ACZ92_17995 | ACZ92_19705 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.758 |
| KOH18053.1 | dnaN | ACZ92_17995 | ACZ92_03385 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.985 |
| KOH18053.1 | mutS | ACZ92_17995 | ACZ92_20960 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA mismatch repair protein MutS; This protein performs the mismatch recognition step during the DNA repair process; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.721 |
| KOH18053.1 | recA | ACZ92_17995 | ACZ92_20950 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.815 |
| KOH18053.1 | xni | ACZ92_17995 | ACZ92_12690 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.968 |
| KOH18127.1 | KOH18053.1 | ACZ92_18405 | ACZ92_17995 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
| KOH18127.1 | KOH20626.1 | ACZ92_18405 | ACZ92_13175 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
| KOH18127.1 | RnhB | ACZ92_18405 | ACZ92_19705 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.450 |
| KOH18127.1 | dnaN | ACZ92_18405 | ACZ92_03385 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.925 |
| KOH18127.1 | recA | ACZ92_18405 | ACZ92_20950 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.809 |
| KOH18127.1 | xni | ACZ92_18405 | ACZ92_12690 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.462 |
| KOH18387.1 | KOH18053.1 | ACZ92_19885 | ACZ92_17995 | DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| KOH18387.1 | KOH20626.1 | ACZ92_19885 | ACZ92_13175 | DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.607 |
| KOH18387.1 | RnhB | ACZ92_19885 | ACZ92_19705 | DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.466 |
| KOH18387.1 | dnaN | ACZ92_19885 | ACZ92_03385 | DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.935 |