STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)    
Predicted Functional Partners:
IspD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
KOH21002.1
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate; Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
  
 0.996
KOH22551.1
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IspG family.
 
  
 0.984
Ipk
Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
truD
Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
    0.983
trmD
Methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.922
KOH18362.1
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.859
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
   
 0.855
KOH21518.1
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.847
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.819
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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