Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KOH18584.1Histidine kinase; Part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; Derived by automated computational analysis using gene prediction method: Protein Homology. (932 aa)    
Predicted Functional Partners:
KOH19631.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.997
sirA
Response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.995
KOH17401.1
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
KOH22352.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.993
KOH19630.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
KOH17491.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.979
KOH20951.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.959
KOH22329.1
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.947
KOH17268.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.947
KOH18730.1
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.946
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
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