Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KOH17244.1Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)    
Predicted Functional Partners:
KOH21926.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.972
KOH19292.1
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.951
KOH18616.1
Catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.934
KOH17203.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.929
KOH24991.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.
   
 
 0.925
KOH25227.1
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.924
KOH22272.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.912
KOH24853.1
ferredoxin-NADP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.849
KOH17867.1
Glucose-6-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.826
KOH21568.1
Iron ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.810
Your Current Organism:
Vibrio parahaemolyticus
NCBI taxonomy Id: 670
Other names: ATCC 17802, Beneckea parahaemolytica, CAIM 320, CCUG 14474, CCUG 15657, CCUG 4224, CIP 75.2, DSM 10027, IFO 12711, LMG 2850, LMG:2850, NBRC 12711, NCCB 77010, NCCB 77018, NCTC 10903, NRRL B-4167, Oceanomonas parahaemolytica, Pasteurella parahaemolytica, V. parahaemolyticus
Server load: low (16%) [HD]