STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM35_000123040ATP-dependent DNA helicase; Belongs to the helicase family. (852 aa)    
Predicted Functional Partners:
TM35_000182660
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.493
TM35_000361740
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.488
TM35_000171820
DNA polymerase alpha subunit B.
   
 
 0.455
TM35_000142980
Anti-silencing protein ASF 1.
   
 
 0.448
TM35_000084690
Uncharacterized protein.
   
 
 0.448
TM35_000311820
ATP-dependent DNA helicase.
  
 
 0.430
TM35_000043230
Structural maintenance of chromosomes protein.
  
 
 0.414
TM35_000182690
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
   
 
  0.406
Your Current Organism:
Trypanosoma theileri
NCBI taxonomy Id: 67003
Other names: T. theileri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.