STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP71574.1Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. (479 aa)    
Predicted Functional Partners:
ANP71665.1
Alpha-ketoglutarate decarboxylase; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
  
 0.999
ANP72655.1
Dihydrolipoamide succinyltransferase; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
 0.958
ANP74708.1
Pyruvate dehydrogenase; Pfam:pfam02779 Transketolase, pyrimidine binding domain.
 0.956
ANP74707.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).
 0.925
ANP74709.1
Pfam:pfam00676 Dehydrogenase E1 component.
 
 0.885
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.840
ANP71573.1
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
  
 0.712
ANP71572.1
Phosphomannomutase; Pfam:pfam02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I.
  
  
 0.704
ANP72799.1
Pfam:pfam00215 Orotidine 5'-phosphate decarboxylase.
      
 0.684
gcvT
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.655
Your Current Organism:
Cryobacterium arcticum
NCBI taxonomy Id: 670052
Other names: C. arcticum, Cryobacterium arcticum Bajerski et al. 2011, Cryobacterium sp. SK1, DSM 22823, NCCB 100316, strain SK1
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