node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANP70996.1 | ANP72569.1 | PA27867_0017 | PA27867_1613 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | 0.999 |
ANP70996.1 | ANP72783.1 | PA27867_0017 | PA27867_1830 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.998 |
ANP70996.1 | ANP73765.1 | PA27867_0017 | PA27867_2827 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Pfam:pfam01063 Aminotransferase class IV. | 0.935 |
ANP70996.1 | ANP74170.1 | PA27867_0017 | PA27867_3240 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Pfam:pfam01817 Chorismate mutase type II. | 0.865 |
ANP70996.1 | aroB | PA27867_0017 | PA27867_1862 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.646 |
ANP70996.1 | aroC | PA27867_0017 | PA27867_1864 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.921 |
ANP70996.1 | trpA | PA27867_0017 | PA27867_1828 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.978 |
ANP70996.1 | trpB | PA27867_0017 | PA27867_1829 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.986 |
ANP70996.1 | trpD | PA27867_0017 | PA27867_1725 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
ANP70996.1 | trpE | PA27867_0017 | PA27867_1833 | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.999 |
ANP72569.1 | ANP70996.1 | PA27867_1613 | PA27867_0017 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Para-aminobenzoate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I. | 0.999 |
ANP72569.1 | ANP72783.1 | PA27867_1613 | PA27867_1830 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.992 |
ANP72569.1 | ANP73765.1 | PA27867_1613 | PA27867_2827 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Pfam:pfam01063 Aminotransferase class IV. | 0.920 |
ANP72569.1 | ANP74170.1 | PA27867_1613 | PA27867_3240 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Pfam:pfam01817 Chorismate mutase type II. | 0.839 |
ANP72569.1 | aroB | PA27867_1613 | PA27867_1862 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.719 |
ANP72569.1 | aroC | PA27867_1613 | PA27867_1864 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.965 |
ANP72569.1 | trpA | PA27867_1613 | PA27867_1828 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.953 |
ANP72569.1 | trpB | PA27867_1613 | PA27867_1829 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.967 |
ANP72569.1 | trpD | PA27867_1613 | PA27867_1725 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.994 |
ANP72569.1 | trpE | PA27867_1613 | PA27867_1833 | Anthranilate synthase; Pfam:pfam00425 chorismate binding enzyme. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.847 |