node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANP73054.1 | ANP73055.1 | PA27867_2102 | PA27867_2103 | Pfam:pfam10611 Protein of unknown function (DUF2469). | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.796 |
ANP73054.1 | ANP73056.1 | PA27867_2102 | PA27867_2104 | Pfam:pfam10611 Protein of unknown function (DUF2469). | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | 0.790 |
ANP73054.1 | rplS | PA27867_2102 | PA27867_2105 | Pfam:pfam10611 Protein of unknown function (DUF2469). | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.621 |
ANP73055.1 | ANP73054.1 | PA27867_2103 | PA27867_2102 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Pfam:pfam10611 Protein of unknown function (DUF2469). | 0.796 |
ANP73055.1 | ANP73056.1 | PA27867_2103 | PA27867_2104 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | 0.948 |
ANP73055.1 | ffh | PA27867_2103 | PA27867_2114 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.554 |
ANP73055.1 | rplS | PA27867_2103 | PA27867_2105 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.771 |
ANP73056.1 | ANP73054.1 | PA27867_2104 | PA27867_2102 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Pfam:pfam10611 Protein of unknown function (DUF2469). | 0.790 |
ANP73056.1 | ANP73055.1 | PA27867_2104 | PA27867_2103 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.948 |
ANP73056.1 | ffh | PA27867_2104 | PA27867_2114 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.625 |
ANP73056.1 | ftsY | PA27867_2104 | PA27867_2119 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.707 |
ANP73056.1 | lepA | PA27867_2104 | PA27867_1623 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.799 |
ANP73056.1 | rplS | PA27867_2104 | PA27867_2105 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.688 |
ANP73056.1 | secA | PA27867_2104 | PA27867_0678 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.741 |
ANP73056.1 | secD | PA27867_2104 | PA27867_1878 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.681 |
ANP73056.1 | secE | PA27867_2104 | PA27867_0299 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.686 |
ANP73056.1 | secY | PA27867_2104 | PA27867_2941 | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.645 |
ffh | ANP73055.1 | PA27867_2114 | PA27867_2103 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.554 |
ffh | ANP73056.1 | PA27867_2114 | PA27867_2104 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Pfam:pfam10502 Signal peptidase, peptidase S26; Belongs to the peptidase S26 family. | 0.625 |
ffh | ftsY | PA27867_2114 | PA27867_2119 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.998 |