STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP73999.1MATE family efflux protein; Pfam:pfam01554 MatE. (481 aa)    
Predicted Functional Partners:
ANP73998.1
Transcriptional regulator; Pfam:pfam12802 MarR family.
 
  
 0.888
ANP72504.1
Pfam:pfam00494 Squalene/phytoene synthase.
   
 
 0.645
ANP72772.1
30S ribosomal protein S1; Pfam:pfam00575 S1 RNA binding domain.
  
    0.600
ANP72262.1
Pfam:pfam00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.548
gap
Pfam:pfam02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.548
ANP73996.1
Transcriptional regulator; Pfam:pfam03976 Polyphosphate kinase 2 (PPK2).
       0.448
ANP73997.1
Carboxymethylenebutenolidase; Pfam:pfam01738 Dienelactone hydrolase family.
       0.431
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.401
Your Current Organism:
Cryobacterium arcticum
NCBI taxonomy Id: 670052
Other names: C. arcticum, Cryobacterium arcticum Bajerski et al. 2011, Cryobacterium sp. SK1, DSM 22823, NCCB 100316, strain SK1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.