node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | PA27867_1848 | PA27867_1847 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | 0.999 |
carA | purD | PA27867_1848 | PA27867_3219 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | 0.681 |
carA | purE | PA27867_1848 | PA27867_0618 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.695 |
carA | purF | PA27867_1848 | PA27867_3207 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.969 |
carA | purH | PA27867_1848 | PA27867_2875 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.687 |
carA | purK | PA27867_1848 | PA27867_0617 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.572 |
carA | purL | PA27867_1848 | PA27867_3236 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Phosphoribosylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...] | 0.607 |
carA | purM | PA27867_1848 | PA27867_3206 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Phosphoribosylaminoimidazole synthetase; Pfam:pfam00586 AIR synthase related protein, N-terminal domain. | 0.705 |
carA | purQ | PA27867_1848 | PA27867_3227 | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.950 |
carB | carA | PA27867_1847 | PA27867_1848 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | 0.999 |
carB | purD | PA27867_1847 | PA27867_3219 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | 0.582 |
carB | purE | PA27867_1847 | PA27867_0618 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.746 |
carB | purF | PA27867_1847 | PA27867_3207 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.979 |
carB | purH | PA27867_1847 | PA27867_2875 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Pfam:pfam01808 AICARFT/IMPCHase bienzyme. | 0.473 |
carB | purL | PA27867_1847 | PA27867_3236 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Phosphoribosylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...] | 0.569 |
carB | purM | PA27867_1847 | PA27867_3206 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Phosphoribosylaminoimidazole synthetase; Pfam:pfam00586 AIR synthase related protein, N-terminal domain. | 0.605 |
carB | purQ | PA27867_1847 | PA27867_3227 | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.940 |
purD | carA | PA27867_3219 | PA27867_1848 | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | Pfam:pfam00988 Carbamoyl-phosphate synthase small chain, CPSase domain; Belongs to the CarA family. | 0.681 |
purD | carB | PA27867_3219 | PA27867_1847 | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family. | 0.582 |
purD | purE | PA27867_3219 | PA27867_0618 | Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family. | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |