node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANP72312.1 | ANP74436.1 | PA27867_1352 | PA27867_3513 | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | 0.686 |
ANP72312.1 | dnaK | PA27867_1352 | PA27867_1228 | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.459 |
ANP72312.1 | dnaK-2 | PA27867_1352 | PA27867_3515 | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.459 |
ANP72312.1 | groL | PA27867_1352 | PA27867_2789 | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.522 |
ANP72312.1 | groS | PA27867_1352 | PA27867_2905 | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.545 |
ANP72312.1 | rplN | PA27867_1352 | PA27867_2950 | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.812 |
ANP74435.1 | ANP74436.1 | PA27867_3512 | PA27867_3513 | Pfam:pfam13411 MerR HTH family regulatory protein. | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | 0.937 |
ANP74435.1 | dnaK | PA27867_3512 | PA27867_1228 | Pfam:pfam13411 MerR HTH family regulatory protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.665 |
ANP74435.1 | dnaK-2 | PA27867_3512 | PA27867_3515 | Pfam:pfam13411 MerR HTH family regulatory protein. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.921 |
ANP74435.1 | groL | PA27867_3512 | PA27867_2789 | Pfam:pfam13411 MerR HTH family regulatory protein. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.627 |
ANP74435.1 | groS | PA27867_3512 | PA27867_2905 | Pfam:pfam13411 MerR HTH family regulatory protein. | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.495 |
ANP74435.1 | grpE | PA27867_3512 | PA27867_1229 | Pfam:pfam13411 MerR HTH family regulatory protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.805 |
ANP74435.1 | grpE-2 | PA27867_3512 | PA27867_3514 | Pfam:pfam13411 MerR HTH family regulatory protein. | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] | 0.954 |
ANP74435.1 | hrcA | PA27867_3512 | PA27867_1628 | Pfam:pfam13411 MerR HTH family regulatory protein. | HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.721 |
ANP74436.1 | ANP72312.1 | PA27867_3513 | PA27867_1352 | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | CoA-disulfide reductase; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase. | 0.686 |
ANP74436.1 | ANP74435.1 | PA27867_3513 | PA27867_3512 | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | Pfam:pfam13411 MerR HTH family regulatory protein. | 0.937 |
ANP74436.1 | dnaK | PA27867_3513 | PA27867_1228 | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.973 |
ANP74436.1 | dnaK-2 | PA27867_3513 | PA27867_3515 | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
ANP74436.1 | groL | PA27867_3513 | PA27867_2789 | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.812 |
ANP74436.1 | groS | PA27867_3513 | PA27867_2905 | Molecular chaperone DnaJ; Pfam:pfam00226 DnaJ domain. | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.682 |