SFR32822.1 protein (Litoreibacter janthinus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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[Homology]

Score

SFR32822.1

DNA-binding transcriptional regulator, MerR family. (141 aa)

Predicted Functional Partners:

SFR32812.1

0.852

SFR35081.1

0.804

SFR32688.1

0.724

SFR32816.1

0.674

SFR40908.1

0.656

SFR55339.1

0.656

rpoB

0.647

SFR32638.1

0.620

SFR35239.1

0.617

SFR41934.1

0.617

Your Current Organism:

Litoreibacter janthinus

NCBI taxonomy Id: 670154
Other names: DSM 26921, JCM 16492, KMM 3842, L. janthinus, Litoreibacter janthinus Romanenko et al. 2011, NRIC 0772, alpha proteobacterium KMM 3842

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFR32638.1	SFR32688.1	SAMN04488002_0172	SAMN04488002_0182	Response regulator receiver domain-containing protein.	PAS domain S-box-containing protein.	0.998
SFR32638.1	SFR32822.1	SAMN04488002_0172	SAMN04488002_0209	Response regulator receiver domain-containing protein.	DNA-binding transcriptional regulator, MerR family.	0.620
SFR32638.1	SFR35081.1	SAMN04488002_0172	SAMN04488002_0583	Response regulator receiver domain-containing protein.	Glutamate synthase (NADPH) large subunit.	0.656
SFR32688.1	SFR32638.1	SAMN04488002_0182	SAMN04488002_0172	PAS domain S-box-containing protein.	Response regulator receiver domain-containing protein.	0.998
SFR32688.1	SFR32822.1	SAMN04488002_0182	SAMN04488002_0209	PAS domain S-box-containing protein.	DNA-binding transcriptional regulator, MerR family.	0.724
SFR32688.1	SFR35081.1	SAMN04488002_0182	SAMN04488002_0583	PAS domain S-box-containing protein.	Glutamate synthase (NADPH) large subunit.	0.660
SFR32688.1	SFR35239.1	SAMN04488002_0182	SAMN04488002_0610	PAS domain S-box-containing protein.	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	0.516
SFR32688.1	SFR41934.1	SAMN04488002_0182	SAMN04488002_1524	PAS domain S-box-containing protein.	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	0.516
SFR32812.1	SFR32816.1	SAMN04488002_0207	SAMN04488002_0208	Cation diffusion facilitator family transporter.	Transglutaminase-like superfamily protein.	0.826
SFR32812.1	SFR32822.1	SAMN04488002_0207	SAMN04488002_0209	Cation diffusion facilitator family transporter.	DNA-binding transcriptional regulator, MerR family.	0.852
SFR32816.1	SFR32812.1	SAMN04488002_0208	SAMN04488002_0207	Transglutaminase-like superfamily protein.	Cation diffusion facilitator family transporter.	0.826
SFR32816.1	SFR32822.1	SAMN04488002_0208	SAMN04488002_0209	Transglutaminase-like superfamily protein.	DNA-binding transcriptional regulator, MerR family.	0.674
SFR32822.1	SFR32638.1	SAMN04488002_0209	SAMN04488002_0172	DNA-binding transcriptional regulator, MerR family.	Response regulator receiver domain-containing protein.	0.620
SFR32822.1	SFR32688.1	SAMN04488002_0209	SAMN04488002_0182	DNA-binding transcriptional regulator, MerR family.	PAS domain S-box-containing protein.	0.724
SFR32822.1	SFR32812.1	SAMN04488002_0209	SAMN04488002_0207	DNA-binding transcriptional regulator, MerR family.	Cation diffusion facilitator family transporter.	0.852
SFR32822.1	SFR32816.1	SAMN04488002_0209	SAMN04488002_0208	DNA-binding transcriptional regulator, MerR family.	Transglutaminase-like superfamily protein.	0.674
SFR32822.1	SFR35081.1	SAMN04488002_0209	SAMN04488002_0583	DNA-binding transcriptional regulator, MerR family.	Glutamate synthase (NADPH) large subunit.	0.804
SFR32822.1	SFR35239.1	SAMN04488002_0209	SAMN04488002_0610	DNA-binding transcriptional regulator, MerR family.	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	0.617
SFR32822.1	SFR40908.1	SAMN04488002_0209	SAMN04488002_1389	DNA-binding transcriptional regulator, MerR family.	(R)-ethylmalonyl-CoA mutase.	0.656
SFR32822.1	SFR41934.1	SAMN04488002_0209	SAMN04488002_1524	DNA-binding transcriptional regulator, MerR family.	Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).	0.617

page 1 of 3

Network Stats

number of nodes:

6

number of edges:

12

average node degree:

4

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.0064

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006526

Arginine biosynthetic process

9 of 14

2.76

9.81

2.88e-20

GO:0046394

Carboxylic acid biosynthetic process

10 of 235

1.58

3.38

2.09e-13

GO:0006591

Ornithine metabolic process

3 of 3

2.95

3.17

1.57e-06

GO:0042450

Arginine biosynthetic process via ornithine

2 of 2

2.95

1.87

0.00040

GO:1901566

Organonitrogen compound biosynthetic process

10 of 576

1.19

1.75

5.53e-10

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003991

Acetylglutamate kinase activity

2 of 2

2.95

1.36

0.0035

GO:0008483

Transaminase activity

2 of 24

1.87

0.7

0.0464

GO:0036094

Small molecule binding

8 of 1136

0.8

0.6

0.0035

GO:0016740

Transferase activity

7 of 1222

0.71

0.46

0.0175

GO:0043168

Anion binding

6 of 1023

0.72

0.41

0.0464

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 2163

0.62

0.51

0.00038

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7435

Arginine biosynthetic process

9 of 12

2.83

10.12

1.29e-20

CL:7439

Arginine biosynthesis

6 of 6

2.95

6.91

1.07e-13

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00220

Arginine biosynthesis

9 of 27

2.47

8.59

2.98e-19

map01210

2-Oxocarboxylic acid metabolism

6 of 52

2.01

3.96

6.63e-10

map01230

Biosynthesis of amino acids

9 of 187

1.63

3.47

1.50e-12

map01110

Biosynthesis of secondary metabolites

9 of 778

1.01

1.19

2.09e-07

map00250

Alanine, aspartate and glutamate metabolism

2 of 41

1.64

0.82

0.0227

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005622

Intracellular

9 of 2422

0.52

0.33

0.0406

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0055

Arginine biosynthesis

5 of 9

2.7

5.02

2.68e-10

KW-0963

Cytoplasm

5 of 265

1.23

1.13

0.00044

KW-0808

Transferase

6 of 489

1.04

0.93

0.00044

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