STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR33344.1Sirohydrochlorin cobaltochelatase. (409 aa)    
Predicted Functional Partners:
SFR33323.1
Cobalt-precorrin 5A hydrolase / precorrin-3B C17-methyltransferase.
  
 0.997
SFR47672.1
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
 
 0.996
SFR39534.1
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
 
 0.991
SFR33328.1
Precorrin-2/cobalt-factor-2 C20-methyltransferase.
 
  
 0.990
SFR33333.1
precorrin-6Y C5,15-methyltransferase (decarboxylating).
 
  
 0.989
SFR33338.1
precorrin-8X methylmutase.
   
 0.984
SFR50465.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.906
SFR33317.1
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase.
 
   
 0.902
SFR33349.1
Hypothetical protein.
       0.846
cbiD
cobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
   
 0.844
Your Current Organism:
Litoreibacter janthinus
NCBI taxonomy Id: 670154
Other names: DSM 26921, JCM 16492, KMM 3842, L. janthinus, Litoreibacter janthinus Romanenko et al. 2011, NRIC 0772, alpha proteobacterium KMM 3842
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