STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGK56201.1Penicillin-binding protein, 1A family; COG0744 Membrane carboxypeptidase (penicillin-binding protein). (758 aa)    
Predicted Functional Partners:
AGK57221.1
Penicillin-binding protein 1A; COG5009 Membrane carboxypeptidase/penicillin-binding protein.
 
 
0.941
AGK58104.1
Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).
  
  
 
0.915
AGK57783.1
Serine-type D-Ala-D-Ala carboxypeptidase; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
   
 
 0.907
AGK56429.1
Peptidoglycan glycosyltransferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
 
 
 0.768
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
  
   
 0.726
AGK56434.1
COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.
  
 
 
 0.725
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.660
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.617
AGK58505.1
(p)ppGpp synthetase I SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
     0.616
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
   
 0.592
Your Current Organism:
Hyphomicrobium denitrificans 1NES1
NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1
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