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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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Score
metHCOG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. (353 aa)    
Predicted Functional Partners:
AGK57840.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
 0.999
AGK57842.1
COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.990
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.953
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.931
AGK58128.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.931
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.919
AGK57643.1
COG2873 O-acetylhomoserine sulfhydrylase.
  
 
 0.917
AGK59979.1
COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family.
  
 
 0.917
fhs
Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.912
fhs-2
Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.912
Your Current Organism:
Hyphomicrobium denitrificans 1NES1
NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1
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