STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AGK58080.1Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (223 aa)    
Predicted Functional Partners:
AGK58079.1
COG0642 Signal transduction histidine kinase.
 
 0.958
AGK57612.1
GAF sensor hybrid histidine kinase; COG2770 FOG: HAMP domain.
  
 
 0.865
AGK56366.1
COG0642 Signal transduction histidine kinase.
 
 0.824
AGK56546.1
COG0642 Signal transduction histidine kinase.
 
 
 0.796
AGK58048.1
COG0642 Signal transduction histidine kinase.
  
 
 0.786
AGK59749.1
Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.
  
   0.779
AGK58633.1
Chemotaxis protein CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.758
AGK58071.1
COG0642 Signal transduction histidine kinase.
 
   0.754
AGK59960.1
PAS/PAC sensor hybrid histidine kinase; COG0642 Signal transduction histidine kinase.
 
 
 0.715
AGK58572.1
COG0642 Signal transduction histidine kinase.
 
 
 0.711
Your Current Organism:
Hyphomicrobium denitrificans 1NES1
NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.