STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGK59460.1LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (223 aa)    
Predicted Functional Partners:
AGK57612.1
GAF sensor hybrid histidine kinase; COG2770 FOG: HAMP domain.
  
 
 0.853
AGK58641.1
COG0642 Signal transduction histidine kinase.
 
 
 0.849
AGK58036.1
COG0642 Signal transduction histidine kinase.
 
 
 0.847
AGK56836.1
COG3850 Signal transduction histidine kinase, nitrate/nitrite-specific.
 
 
 0.805
AGK57600.1
LuxR family two component transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
     0.773
AGK57505.1
LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
     0.735
AGK58633.1
Chemotaxis protein CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
0.641
AGK58143.1
PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; COG2199 FOG: GGDEF domain.
 
 
 0.539
AGK56944.1
COG4566 Response regulator.
  
   
 0.492
AGK59459.1
COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.
       0.422
Your Current Organism:
Hyphomicrobium denitrificans 1NES1
NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.