STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGK59636.1Ammonium transporter; COG0004 Ammonia permease. (402 aa)    
Predicted Functional Partners:
AGK58479.1
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 
 0.990
AGK59646.1
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
 
 0.989
AGK59046.1
COG0067 Glutamate synthase domain 1.
 
  
 0.766
AGK59197.1
Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
      0.721
AGK57735.1
COG3852 Signal transduction histidine kinase, nitrogen specific.
  
 
 0.619
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.515
AGK58633.1
Chemotaxis protein CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
 0.455
AGK59350.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.
  
  
 0.450
AGK58143.1
PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; COG2199 FOG: GGDEF domain.
    
 0.446
gltD
COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
 
  
 0.435
Your Current Organism:
Hyphomicrobium denitrificans 1NES1
NCBI taxonomy Id: 670307
Other names: H. denitrificans 1NES1, Hyphomicrobium denitrificans str. 1NES1, Hyphomicrobium denitrificans strain 1NES1
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