STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPL_05185C2 domain-containing protein. (955 aa)    
Predicted Functional Partners:
sec1
Sec1-like family protein; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.877
syn1A
t-SNARE family protein; Belongs to the syntaxin family.
    
 0.851
PPL_09243
Ras GTPase domain-containing protein.
   
 
 0.841
sybB
Synaptobrevin domain-containing protein.
    
 0.839
PPL_10264
Uncharacterized protein.
   
 
 0.819
PPL_00848
MFS domain-containing protein.
     
 0.707
PPL_02341
MFS transporter.
     
 0.707
PPL_10941
Protein kinase domain-containing protein.
   
 
 0.689
PPL_07798
MFS domain-containing protein.
     
 0.674
PPL_00145
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]
     
 0.659
Your Current Organism:
Heterostelium album
NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.