STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPL_12599Histidine triad family protein. (471 aa)    
Predicted Functional Partners:
xrcc1
BRCT domain-containing protein.
   
 0.998
lig3
DNA ligase.
  
 0.890
PPL_00831
SMAD/FHA domain-containing protein.
  
 0.888
PPL_01390
DNA repair metallo-beta-lactamase domain-containing protein.
  
 0.865
PPL_00073
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
   
 0.858
PPL_12018
POLXc domain-containing protein.
   
 0.858
lig4
DNA ligase.
  
 0.849
PPL_01939
Uncharacterized protein.
    
 
 0.787
PPL_08045
Uncharacterized protein.
 
  
 
 0.787
PPL_11123
Protein-tyrosine phosphatase 3.
    
 
 0.787
Your Current Organism:
Heterostelium album
NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500
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