STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pikEPhosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (704 aa)    
Predicted Functional Partners:
vps15
Uncharacterized protein.
   
 0.996
PPL_00529
Uncharacterized protein.
   
 0.996
PPL_08965
Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.963
pten
Protein tyrosine phosphatase.
    
 0.960
sac1
Putative phosphoinositide phosphatase.
    
 0.960
rab5A
Rab GTPase.
    
 0.958
PPL_02243
Phosphatidylinositol 4-kinase; Belongs to the PI3/PI4-kinase family.
     
0.957
pip5k3
FYVE-type zinc finger-containing protein.
     
 0.945
PPL_05282
Sac domain-containing inositol phosphatase 3.
   
 
 0.945
PPL_06413
LIM-type zinc finger-containing protein.
    
 0.940
Your Current Organism:
Heterostelium album
NCBI taxonomy Id: 670386
Other names: H. album PN500, Heterostelium album PN500, Heterostelium pallidum PN500, Polysphondylium pallidum PN500
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.