STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDE88173.1DNA topoisomerase-3. (746 aa)    
Predicted Functional Partners:
SDF85186.1
ATP-dependent DNA helicase, RecQ-like.
 
 
 0.897
SDF83427.1
HRDC domain-containing protein.
  
 0.847
SDG04230.1
Glutamate synthase (ferredoxin).
  
  
 0.754
SDE78657.1
Exonuclease SbcC.
  
 0.628
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.611
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.607
leuS
leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.607
SDF47929.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.604
SDE88202.1
Glutamate synthase (NADPH/NADH) small chain.
       0.549
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.527
Your Current Organism:
Fontibacillus panacisegetis
NCBI taxonomy Id: 670482
Other names: CECT 7605, DSM 28129, F. panacisegetis, Fontibacillus panacisegetis Lee et al. 2011, KCTC 13564, Paenibacillus sp. KCTC 13564, strain P11-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.