STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S7PT52_GLOTARibonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (880 aa)    
Predicted Functional Partners:
S7QIX6_GLOTA
Ribonucleotide reductase R2 subunit variant.
  
 0.998
S7QIZ1_GLOTA
Uncharacterized protein.
  
 0.998
S7RPA9_GLOTA
Guanylate kinase.
    
 0.978
S7QBG2_GLOTA
Thymidylate kinase.
  
 
 0.975
S7QFC4_GLOTA
Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
    
 0.975
S7QGU8_GLOTA
Nucleoside diphosphate kinase.
    
 0.975
S7S4I3_GLOTA
Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
   
 
  0.972
S7QF77_GLOTA
Adenylate kinase; Belongs to the adenylate kinase family.
    
 0.968
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
    
 0.968
S7QNA7_GLOTA
DNA helicase; Belongs to the MCM family.
   
 
 0.938
Your Current Organism:
Gloeophyllum trabeum
NCBI taxonomy Id: 670483
Other names: G. trabeum ATCC 11539, Gloeophyllum trabeum ATCC 11539
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.