STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADR35476.1Metal dependent phosphohydrolase; COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006674: IPR006675; KEGG: ttj:TTHA1791 hydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Putative hydrolase (HD domain); TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (191 aa)    
Predicted Functional Partners:
lysS
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR002313: IPR006195: IPR018149: IPR004365: IPR 004364; KEGG: ttj:TTHA1041 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial; Belongs to the class-II aminoacyl-tRNA synthetase family.
      0.911
ADR35474.1
Phenazine biosynthesis protein PhzF family; COGs: COG0384 epimerase PhzC/PhzF homolog; InterPro IPR003719; KEGG: sus:Acid_1799 PhzF family phenazine biosynthesis protein; PFAM: Phenazine biosynthesis PhzC/PhzF protein; SPTR: Phenazine biosynthesis protein PhzF family; TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis-like protein; TIGRFAM: phenazine biosynthesis protein PhzF family.
       0.562
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.562
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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