STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR35500.1Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR008250: IPR005834: IPR001757: IPR 001366: IPR006404: IPR006416: IPR001969: IPR018303: IPR017969:I PR000150; KEGG: msv:Mesil_1627 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily [...] (686 aa)    
Predicted Functional Partners:
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.798
ADR35501.1
Transcriptional regulator, ArsR family; InterPro IPR001845: IPR018334; KEGG: ttj:TTHA0705 transcriptional repressor SmtB; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional repressor smtB; PFAM: Bacterial regulatory protein, arsR family.
 
  
 0.737
ADR37504.1
InterPro IPR006121: IPR017969; KEGG: ttj:TTHA1718 heavy metal binding protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein; PFAM: Heavy-metal-associated domain.
  
 
 0.682
ADR36367.1
Hypothetical protein; InterPro IPR006121; KEGG: msv:Mesil_2125 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.658
ADR36008.1
COGs: COG2132 Putative multicopper oxidase; InterProIPR006311: IPR011707: IPR001117: IPR011706: IPR 017909: IPR002355; KEGG: ter:Tery_0359 multicopper oxidase, type 3; PFAM: multicopper oxidase type 3; multicopper oxidase type 1; multicopper oxidase type 2; SPTR: Laccase; PFAM: Multicopper oxidase.
 
  
 0.423
ADR35502.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: kra:Krad_2728 alpha/beta hydrolase fold; PFAM: alpha/beta hydrolase fold; SPTR: Acylhomoserine lactonase; PFAM: alpha/beta hydrolase fold.
       0.405
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.