Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADR35740.1Protein of unknown function DUF437; InterPro IPR007374; KEGG: ttj:TTHA0113 hypothetical protein; PFAM: protein of unknown function DUF437; SPTR: Hypothetical conserved protein; PFAM: ASCH domain. (128 aa)    
Predicted Functional Partners:
ADR35739.1
ABC transporter related protein; COGs: COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain; InterPro IPR000182: IPR003439: IPR003593; KEGG: ttj:TTHA0114 ABC transporter ATP-binding protein; PFAM: ABC transporter related; GCN5-related N-acetyltransferase; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; Acetyltransferase (GNAT) family.
 
      0.898
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.567
ADR35742.1
Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: msv:Mesil_0025 protein of unknown function DUF164; PFAM: protein of unknown function DUF164; SPTR: Putative uncharacterized protein; PFAM: Putative zinc ribbon domain.
       0.539
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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