STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR35858.1COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: sli:Slin_3239 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold. (267 aa)    
Predicted Functional Partners:
ADR37259.1
Metallophosphoesterase; InterPro IPR004843; KEGG: msv:Mesil_2612 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
    
  0.788
ADR35861.1
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839; KEGG: msv:Mesil_3402 hypothetical protein; PFAM: aminotransferase class I and II; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class I and II.
     
 0.775
cbiA
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
       0.773
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.773
ADR35855.1
ABC transporter related protein; COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439: IPR017871: IPR003593; KEGG: tth:TTC0392 iron(III) dicitrate transport ATP-binding protein FecE; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Iron(III) dicitrate transport ATP-binding protein fecE; PFAM: ABC transporter.
  
    0.771
ADR35854.1
COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: ttj:TTHA0747 iron ABC transporter, permease protein; PFAM: transport system permease protein; SPTR: Transport system permease protein; PFAM: FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.768
ADR35856.1
KEGG: mrb:Mrub_0232 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
ADR35857.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: tra:Trad_0380 cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase.
       0.768
ADR35853.1
Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: ttj:TTHA0746 iron ABC transporter, substrate-binding protein; PFAM: periplasmic binding protein; SPTR: Iron ABC transporter, substrate-binding protein; PFAM: Periplasmic binding protein.
       0.767
ADR35863.1
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078: IPR001345; KEGG: mrb:Mrub_0234 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family.
   
   0.703
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
Server load: low (16%) [HD]