Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADR35940.1Protein of unknown function DUF72; COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: pmx:PERMA_0651 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF72. (240 aa)    
Predicted Functional Partners:
ADR35941.1
NUDIX hydrolase; InterPro IPR000086: IPR020476: IPR020084; KEGG: gob:Gobs_5080 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
       0.773
ADR35939.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094: IPR004113: IPR016166; KEGG: mrb:Mrub_2162 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
       0.565
cobB
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: msv:Mesil_0952 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; manually curated; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
      0.548
ADR35946.1
DNA polymerase LigD, polymerase domain protein; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR014145: IPR002755; KEGG: sti:Sthe_0314 DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit; SPTR: DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain.
 
    0.533
ADR35942.1
Cytochrome c oxidase subunit II; InterPro IPR002429; KEGG: pjd:Pjdr2_4978 hypothetical protein; PFAM: cytochrome c oxidase subunit II; SPTR: Cytochrome c oxidase, subunit II; PFAM: Cytochrome C oxidase subunit II, periplasmic domain.
       0.460
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
    0.434
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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