STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR36248.1Cupin 2 conserved barrel domain protein; COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: ttj:TTHA1461 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Putative uncharacterized protein; PFAM: Cupin domain. (124 aa)    
Predicted Functional Partners:
ADR36247.1
COGs: COG1926 phosphoribosyltransferase; InterPro IPR000836; KEGG: msv:Mesil_1594 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain.
       0.779
ADR36246.1
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR001808: IPR012318; KEGG: tra:Trad_0639 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain.
  
    0.567
ADR35873.1
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524: IPR011663; KEGG: msv:Mesil_2586 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
  
    0.457
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.