STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR36410.1FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0492 Thioredoxin reductase; InterPro IPR000103: IPR013027; KEGG: ttj:TTHA1215 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Probable thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. (323 aa)    
Predicted Functional Partners:
ADR37581.1
COGs: COG0492 Thioredoxin reductase; InterPro IPR008255: IPR005982: IPR000103: IPR013027; KEGG: ttj:TTHA1920 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
  
 
0.910
ADR36870.1
COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ttj:TTHA1735 iron-sulfur cluster biosynthesis protein IscS (cysteine desulfurase); PFAM: aminotransferase class V; SPTR: Cysteine desulfhydrase/selenocysteine lyase; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
  
 
  0.905
ADR37031.1
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: tra:Trad_2517 Cys/Met metabolism pyridoxal-phosphate-dependent protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: methionine gamma-lyase.
   
 
 0.905
ADR37351.1
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017936: IPR017937: IPR005746: IPR013766: IPR 006662; KEGG: msv:Mesil_3022 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.880
bshC
Protein of unknown function UCP012535; COGs: COG4365 conserved hypothetical protein; InterPro IPR011199; KEGG: msv:Mesil_2832 protein of unknown function UCP012535; PFAM: protein of unknown function UCP012535; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2317); Belongs to the BshC family.
  
   
 0.702
ADR37030.1
3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.690
ADR36034.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: tth:TTC0745 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1.
  
   
 0.683
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
  
 0.661
ADR37687.1
KEGG: msv:Mesil_3187 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.558
ADR36025.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006122: IPR006403: IPR006416: IPR001757: IPR 006121: IPR008250: IPR005834: IPR002109: IPR001756: IPR001877:I PR018303: IPR017969; KEGG: dge:Dgeo_2553 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; glutaredoxin; SPTR: ATPase, P type cation/copper-transporter; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; copper ion binding pro [...]
  
 
 0.513
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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