Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADR36416.1COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: msv:Mesil_1551 transcriptional regulator, HxlR family; PFAM: helix-turn-helix HxlR type; SPTR: Transcriptional regulator, HxlR family; PFAM: HxlR-like helix-turn-helix. (95 aa)    
Predicted Functional Partners:
ADR36417.1
Zinc/iron permease; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: ttj:TTHA1706 putative divalent heavy-metal cation transporter; PFAM: zinc/iron permease; SPTR: Zinc/iron permease; PFAM: ZIP Zinc transporter.
       0.620
ADR36415.1
KEGG: msv:Mesil_1550 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.557
ADR36414.1
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098: IPR006099; KEGG: ttj:TTHA1246 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain.
       0.550
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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