Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADR36430.1UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594: IPR007901; KEGG: mrb:Mrub_1727 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: UBA/THIF-type NAD/FAD binding protein; manually curated; PFAM: MoeZ/MoeB domain; ThiF family. (266 aa)    
Predicted Functional Partners:
ADR35808.1
Molybdopterin synthase subunit MoaE;molybdopterin synthase subunit MoaD; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003749: IPR003448; KEGG: tth:TTC1947 molybdopterin (MPT) converting factor, subunit 2; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein; SPTR: Molybdopterin converting factor, subunit 1; PFAM: ThiS family; MoaE protein; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal.
 
 0.999
ADR36954.1
COGs: COG1977 Molybdopterin converting factor small subunit; InterPro IPR003749: IPR015272: IPR010038; KEGG: ttj:TTHA0151 molybdopterin converting factor, subunit 1 (MoaD); PFAM: thiamineS protein; protein of unknown function DUF1952; SPTR: Molybdopterin converting factor, subunit 1 (MoaD); TIGRFAM: MoaD family protein; PFAM: ThiS family; Domain of unknown function (DUF1952); TIGRFAM: MoaD family protein, archaeal.
 
 0.982
ADR36429.1
Mov34/MPN/PAD-1 family protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; KEGG: msv:Mesil_2119 Mov34/MPN/PAD-1 family protein; SPTR: Mov34/MPN/PAD-1 family protein.
 
 
 0.952
ADR36127.1
Thiamine biosynthesis protein ThiS; InterPro IPR010035: IPR003749; KEGG: ttj:TTHA0476 hypothetical protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
  
 
 0.940
ADR36965.1
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041: IPR017896: IPR006058: IPR017900: IPR 017907: IPR004489; KEGG: tth:TTC1089 succinate dehydrogenase iron-sulfur subunit; PFAM: ferredoxin; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
      0.650
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
  0.649
ADR35520.1
Galanin; KEGG: pmf:P9303_21011 galanin; SPTR: Possible Galanin; PFAM: Protein of unknown function (DUF3137).
  
  
 0.606
ADR35521.1
Hypothetical protein; KEGG: pmf:P9303_21011 galanin; SPTR: Possible Galanin; PFAM: Protein of unknown function (DUF3137).
  
  
 0.606
ADR35473.1
KEGG: msv:Mesil_0826 transcriptional activator, TenA family; SPTR: Transcriptional activator, TenA family.
  
  
 0.587
ADR36428.1
COGs: COG0480 Translation elongation factors (GTPase); InterProIPR005225: IPR000795: IPR004161: IPR005517: IPR 000640; KEGG: ttj:TTHA1498 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: Elongation factor G (EF-G-2); TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-bin [...]
  
   0.568
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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