STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADR36462.1Histidine kinase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594: IPR005467: IPR011712; KEGG: tth:TTC0158 two-component sensor; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: Probable two-component sensor; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (361 aa)    
Predicted Functional Partners:
ADR36461.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: tth:TTC0157 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Probable two-component response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.966
ADR36179.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: ttj:TTHA1352 response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Transcriptional regulatory protein; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 0.895
ADR35887.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: tra:Trad_1782 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 0.861
ADR36891.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sml:Smlt2299 putative response regulator protein LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Putative response regulator protein LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.857
ADR36699.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: msv:Mesil_2373 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 0.824
ADR36463.1
FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR004821: IPR002606: IPR015864: IPR015865; KEGG: ttj:TTHA0527 riboflavin kinase/FMN adenylyltransferase; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family.
       0.671
ADR36464.1
NUDIX hydrolase; InterPro IPR000086; KEGG: mrb:Mrub_0995 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: NUDIX hydrolase; PFAM: NUDIX domain.
       0.671
ADR36457.1
KEGG: tth:TTC0153 hypothetical protein; SPTR: Hypothetical membrane spanning protein.
       0.517
ADR36458.1
NrfC protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896: IPR017900; KEGG: tth:TTC0154 NrfC protein; SPTR: NrfC protein.
       0.517
ADR36459.1
Molybdopterin oxidoreductase; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR006311: IPR017909: IPR006963: IPR006656: IPR 006657; KEGG: tth:TTC0155 thiosulfate reductase precursor; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Thiosulfate reductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; Belongs to the prokaryotic molybd [...]
       0.517
Your Current Organism:
Oceanithermus profundus
NCBI taxonomy Id: 670487
Other names: O. profundus DSM 14977, Oceanithermus profundus DSM 14977, Oceanithermus profundus str. DSM 14977, Oceanithermus profundus strain DSM 14977
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